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Learning to Have End of Life Conversations Using Artificial Intelligence

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As many as 68 percent of late-stage cancer patients leave their doctor’s offices either underestimating the severity of their disease, overestimating their life expectancy—or both. These misunderstandings can hinder the ability of patients and their families to make realistic decisions about whether to continue aggressive treatments or instead turn to palliative care.

To address the problem, University of Rochester computer scientists, palliative care specialists, and practicing oncologists are perfecting SOPHIE (Standardized Online Patient for Healthcare Interaction Education)—an online virtual “patient” that helps physicians practice how to communicate effectively with late-stage cancer patients about their disease.
Effective communication in this context often means demonstrating empathy and understanding of the complex emotions patients are experiencing.

“During difficult conversations about facing the potential of one’s own death, patients are frightened and don’t know how to ask the right questions, and clinicians may oversimplify, omit, or sugar-coat information, or feel too pressed for time to address patients’ emotions,” says Ehsan Hoque, an associate professor of computer science at Rochester’s Hajim School of Engineering and Applied Sciences. The COVID-19 pandemic has made effective communication even more difficult by causing increasing reliance on virtual rather than in-person interactions between patients and physicians, adds Hoque.

Hoque DELETED REFERENCE TO HIS DATA SCIENCE AFFILIATION, NO LONGER APPLIES is a pioneer in the area of research that shows it is possible for people to learn and improve their social and interpersonal skills by interacting with automated systems. For example, he helped develop LISSA (Live Interactive Social Skills Assistant)—a tool that’s been used effectively by people on the autism spectrum—in collaboration with professor of computer science Len Schubert.

SOPHIE is possible because of a body of nearly 400 conversations that were recorded between late-stage cancer patients and their oncologists, and initially analyzed by palliative care expert Ronald Epstein and his collaborators at the University of Rochester Medical Center. Epstein’s Center for Communication and Disparities Research focuses on how to improve communication between clinicians, patients, and their loved ones.

A paper in IEEE Transactions on Affective Computing describes how lead author Mohammad Rafayet Ali, a postdoctoral researcher, and PhD student Taylan Sen, both members of Hoque’s Rochester Human-Computer Interaction (ROC HCI) Lab, created algorithms that could be applied to the transcripts of these conversations, so the researchers could develop metrics to assess a physician’s ability to communicate clearly with patients.

The metrics focus specifically on the extent that physicians engage in lecturing—delivering a lot of information without giving the patient a chance to ask questions or to respond—or, on the plus side, how well they employ “sentiment trajectory”—using positive words and phrases in ways associated with increased patient understanding.

The researchers used a physician communication training protocol, developed by Epstein and his collaborators, to script SOPHIE’s practice sessions, and enlisted nine practicing oncologists at the University to try out the system.

“We received a lot of feedback from the doctors on how natural the conversation was, the kinds of questions SOPHIE should ask, and the concerns a typical patient might raise,” Ali says.

“In our prior research, physicians practiced with trained actors to learn how to bring up difficult issues, such as prognosis and end of life care,” Epstein says. “But actors can be costly. The online format can provide training at a fraction of the cost and be made available to physicians worldwide. And Ehsan Hoque’s group is on the cutting edge.”

The researchers are now fine-tuning SOPHIE. “Our hope is that once we have demonstrated its efficacy through a randomized controlled experiment, first-year students at the Medical Center can practice with it,” Hoque says.

The demo has been designed to be available through a computer browser, allowing physicians from anywhere around the world to practice their skills live and receive feedback on their speaking rate, turn-taking, type of questions asked and sentiment trajectory.

Other collaborators coauthors of the paper include Thomas Carroll, associate professor of medicine; Lenhart Schubert, professor of computer science; Benjamin Kane (advised by Schubert); and Shagun Bose, an undergraduate researcher in the Hoque lab.

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