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Snip, snip, cure: correcting defects in the genetic blueprint

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Gene editing using ‘molecular scissors’ that snip out and replace faulty DNA could provide an almost unimaginable future for some patients: a complete cure. Cambridge researchers like Dr Alasdair Russell from the Cancer Research UK Cambridge Institute are working towards making the technology cheap and safe, as well as examining the ethical and legal issues surrounding one of the most exciting medical advances of recent times.

“It’s like rewriting DNA with precision,” explains Dr Alasdair Russell. “Unlike other forms of gene therapy, in which cells are given a new working gene but without being able to direct where it ends up in the genome, this technology changes just the faulty gene. It’s precise and it’s ‘scarless’ in that no evidence of the therapy is left within the repaired genome.”

Read more: http://www.cam.ac.uk/research/features/snip-snip-cure-correcting-defects-in-the-genetic-blueprint
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Academic
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