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T-cell assassins captured on film hunting down cancer cells and ‘reloading’ to kill again

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Cambridge researchers have captured on film the activity of T cells – an important component of our immune system – as they hunt down and kill cancer cells. For the first time, they have also shown how these cells reload their toxic weapons.

Cytotoxic T cells are specialist white blood cells that are trained by our immune system to recognise and eliminate threats – including tumour cells and cells infected with invading viruses, such as SARS-CoV-2, which causes COVID-19. They are also at the heart of new immunotherapies that promise to transform cancer treatment.
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Academic
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