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The self-defence force awakens

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An army of cells constantly patrols within us, attacking anything it recognises as foreign, keeping us safe from invading pathogens. Among these, T-cells are the body’s serial killers, patrolling, identifying and destroying infected and cancer cells with remarkable precision and efficiency. They have to contend with cancer cells that are able to trick them by sending out a ‘don’t kill’ signal.

“My lab focuses on what tells a T-cell to kill, and how you make it a really good killer, using imaging and genetic approaches to understand how these cells can be fine-tuned,” says Professor Gillian Griffiths, Director of the Cambridge Institute for Medical Research. “This has revealed some novel mechanisms that play key roles in regulating killing.”

Read more: http://www.cam.ac.uk/research/features/the-self-defence-force-awakens
Category
Academic
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